"The Signaling Petri Net: Predicting Cellular Signaling Network Dynamics without Kinetic Details"

Derek Ruths, Rice University

...In my talk, I will present a new method that predicts the dynamics of cellular signaling networks without requiring any kinetic parameters. Using the connectivity of a signaling network and a simply trained model of constitutively active/inactive proteins, the signaling Petri net (SPN) simulator can predict the qualitative characteristics of a signaling network's dynamics...